There are two coworking spaces right across the street from each other near the Aquarium.
Spark Charleston - seems a bit more geared to the smaller startups.
The Flagship - this one is run by the city of Charleston's Digital Corridor and is geared a bit more to those startups that are a little farther along and in the growth stage. It's mostly private offices, but there is some space for short terms and daily drop-ins. Flagship is planning to open a second location soon as well.
Hi, I'm looking to become a Space Catalyst in Charleston, SC (or, honestly, Columbia, SC -- I'm personally flexible but have to pick a single location, which will likely be based on interest). I've not started doing any legwork, but want to gauge interest. Don't want to move forward on a space too small or too large. Charleston's not exactly a tech-heavy location, so it will be a location geared equally towards techies and small businesses located somewhere in the downtown area.
If you're interested, email me at admin at schrodingerslab.com with your info/preferences/needs/availability/etc..